There are three things from your normal ADV gear that may need to be swapped out for long distance travel:
Tires. Aggressive tires work great for ADV riding and are the choice for many, but for long distance travel does longevity surpass the need for traction? How do you decide what tires to run on any given trip?
Boots. Heavy, tall, well supported motorcycle boots are paramount for protecting your feet and lower leg, but with the limited space available for long distance travel can you really afford to take them along?
Helmets. For ADV riding around home a peaked visor style helmet is the choice for many riders, even with room for goggles. When it comes to long distance travel, do you or would you prefer other features?

LINKS:

Sam Manicom:
BMW Motorcyclists of America – The 50th National Rally 8-10th of June – Doswell, Virginia. Presenting and Book Signing 
BMW Motorcycles of Detroit Saturday June 17th  Presentation Evening and Book signing. .
Chicago Region BMW Motorcycle Owners Assn June 22nd Presentation and Book signing evening. 
Moon Motorsports Monticello Minnesota USA Join us on Saturday 24th of June  Presentation evening and Book signing
Kissell Motorsports Soggy Bottom MotoFest 27th to 30th of July in Port Matilda Pennsylvania USA – Presentation and Booksigning
Mortons BMW 5th of August in Fredericksburg VA – Presentation and Booksigning

Sam Manicom’s spare tyre carrier mods: